simulation of metabolism, drug dosage

[gusl]

On-line Pharmacokinetic Simulation, and the course Basic Principles of Dose Optimization

Computer Simulation and Drug Design

Knowledge-Based Simulation of DNA Metabolism
: "An automated simulation of metabolism can play a role analogous to that of ...
solution of systems of differential equations"
Qualitative Simulation of Large and Complex Genetic Regulatory Systems

btw, when I don't quote a paper here, that usually means I haven't read it thoroughly enough to judge it.

Thank you, Google.